O'Brate, Aurora: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Chemical synthesis and biological evaluation of novel epothilone B and trans-12,13-cyclopropyl epothilone B analogues

K.C Nicolaou, Andreas Ritzén, Kenji Namoto, Rubén M Buey, J.Fernando Dı́az, José M Andreu, Markus Wartmann, Karl-Heinz Altmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Year:

2002

Language:

english

File:

PDF, 617 KB

english, 2002

2

Design, Synthesis, and Biological Properties of Highly Potent Epothilone B Analogues

K. C. Nicolaou, Pradip K. Sasmal, Gerasimos Rassias, Mali Venkat Reddy, Karl-Heinz Altmann, Markus Wartmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

3

Design, Synthesis, and Biological Properties of Highly Potent Epothilone B Analogues

K. C. Nicolaou, Pradip K. Sasmal, Gerasimos Rassias, Mali Venkat Reddy, Karl-Heinz Altmann, Markus Wartmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

4

Total Synthesis and Biological Evaluation of (−)Apicularen A and Analogues Thereof

K. C. Nicolaou, David W. Kim, Rachid Baati, Aurora O′Brate, Paraskevi Giannakakou

Journal:

Chemistry - A European Journal

Year:

2003

Language:

english

File:

PDF, 406 KB

english, 2003

5

Chemical Synthesis and Biological Evaluation of Novel Epothilone B and trans-12,13-Cyclopropyl Epothilone B Analogues.

K. C. Nicolaou, Andreas Ritzen, Kenji Namoto, Ruben M. Buey, J. Fernando Diaz, Jose M. Andreu, Markus Wartmann, Karl-Heinz Altmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Year:

2002

File:

PDF, 25 KB

2002

6

Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation.

K. C. Nicolaou, Yiwei Li, Kazuyuki Sugita, Holger Monenschein, Prasuna Guntupalli, Helen J. Mitchell, Konstantina C. Fylaktakidou, Dionisios Vourloumis, Paraskevi Giannakakou, Aurora O'Brate

Journal:

Year:

2004

File:

PDF, 50 KB

2004

7

Total Synthesis and Biological Evaluation of (-)-Apicularen A and Analogues Thereof

K. C. Nicolaou, David W. Kim, Rachid Baati, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Year:

2004

File:

PDF, 60 KB

2004

8

Studies Toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure.

K. C. Nicolaou, Scott A. Snyder, Nicolas Giuseppone, Xianhai Huang, Marco Bella, Mali V. Reddy, Paraselli Bheema Rao, Alexandros E. Koumbis, Paraskevi Giannakakou, Aurora O'Brate

Journal:

Year:

2004

File:

PDF, 8 KB

2004

9

Molecular Design and Chemical Synthesis of a Highly Potent Epothilone

K. C. Nicolaou, Benjamin A. Pratt, Stellios Arseniyadis, Markus Wartmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

10

Cover Picture: Molecular Design and Chemical Synthesis of a Highly Potent Epothilone (ChemMedChem 1/2006)

K. C. Nicolaou, Benjamin A. Pratt, Stellios Arseniyadis, Markus Wartmann, Aurora O'Brate, Paraskevi Giannakakou

Journal:

Year:

2006

File:

PDF, 45 KB

2006

11

Interaction of Epothilone Analogs with the Paclitaxel Binding Site: Relationship between Binding Affinity, Microtubule Stabilization, and Cytotoxicity

Rubén M. Buey, J.Fernando Dı́az, José M. Andreu, Aurora O'Brate, Paraskevi Giannakakou, K.C. Nicolaou, Pradip K. Sasmal, Andreas Ritzén, Kenji Namoto

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

12

Pharmacogenomic research and serum DNA analysis in the treatment of non-small cell lung cancer

Rafael Rosell, Aurora O'Brate, Mariano Monzó, José Miguel Sánchez, Mónica Guillot, Jacek Jassem, José Javier Sánchez, Albert Abad, Daniel Escuin, Miquel Tarón, Ewa Jassem

Journal:

Clinical and Translational Oncology

Year:

2001

Language:

english

File:

PDF, 149 KB

english, 2001

13

The importance of p53 location: nuclear or cytoplasmic zip code?

Aurora O’Brate, Paraskevi Giannakakou

Journal:

Drug Resistance Updates

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

14

Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure

Nicolaou, K. C., Snyder, Scott A., Giuseppone, Nicolas, Huang, Xianhai, Bella, Marco, Reddy, Mali V., Rao, Paraselli Bheema, Koumbis, Alexandros E., Giannakakou, Paraskevi, O'Brate, Aurora

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 304 KB

english, 2004

15

Total Synthesis of Apoptolidin: Completion of the Synthesis and Analogue Synthesis and Evaluation

Nicolaou, K. C., Li, Yiwei, Sugita, Kazuyuki, Monenschein, Holger, Guntupalli, Prasuna, Mitchell, Helen J., Fylaktakidou, Konstantina C., Vourloumis, Dionisios, Giannakakou, Paraskevi, O'Brate, Aurora

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 670 KB

english, 2003

16

The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Activity †

Pryor, Donald E., O'Brate, Aurora, Bilcer, Geoffrey, Díaz, J. Fernando, Wang, Yuefang, Wang, Yong, Kabaki, Mikio, Jung, M. Katherine, Andreu, José M., Ghosh, Arun K., Giannakakou, Paraskevi, Hamel, Er

Journal:

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

17

Studies toward Diazonamide A: Development of a Hetero-Pinacol Macrocyclization Cascade for the Construction of the Bis-Macrocyclic Framework of the Originally Proposed Structure [ J. Am. Chem. Soc. 2004 , 126 , 10174−10182].

Nicolaou, K. C., Snyder, Scott A., Giuseppone, Nicolas, Huang, Xianhai, Bella, Marco, Reddy, Mali V., Bheema Rao, Paraselli, Koumbis, Alexandros E., Giannakakou, Paraskevi, O'Brate, Aurora

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 12 KB

english, 2004

18

Discovery of a Biologically Active Thiostrepton Fragment

Nicolaou, K. C., Zak, Mark, Rahimipour, Shai, Estrada, Anthony A., Lee, Sang Hyup, O'Brate, Aurora, Giannakakou, Paraskevi, Ghadiri, M. Reza

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 85 KB

english, 2005

19

Resistance to Microtubule-Stabilizing Drugs Involves Two Eventse: β-Tubulin Mutation in One Allele Followed by Loss of the Second Allele

Wang, Yuefang, O’Brate, Aurora, Zhou, Wei, Giannakakou, Paraskevi

Journal:

Year:

2005

Language:

english

File:

PDF, 919 KB

english, 2005

20

Translational oncogenomics: toward rational therapeutic decision-making

Rosell, Rafael, Monzo, Mariano, O'Brate, Aurora, Taron, Miquel

Journal:

Current Opinion in Oncology

Year:

2002

Language:

english

File:

PDF, 444 KB

english, 2002

21

Predictive molecular markers in non–small cell lung cancer

Rosell, Rafael, Tarón, Miquel, O’Brate, Aurora

Journal:

Current Opinion in Oncology

Year:

2001

Language:

english

File:

PDF, 109 KB

english, 2001

22

Paclitaxel Resistance in Non–Small-Cell Lung Cancer Associated With Beta-Tubulin Gene Mutations

Monzó, Mariano, Rosell, Rafael, Sánchez, José Javier, Lee, Jin S., O'Brate, Aurora, González-Larriba, José Luis, Alberola, Vicente, Lorenzo, Juan Carlos, Núñez, Laura, Ro, Jae Y., Martín, Cristina

Journal:

Journal of Clinical Oncology

Year:

1999

Language:

english

File:

PDF, 178 KB

english, 1999